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Article

Single-Cell Transcriptomic Analysis of Ecosystems in Papillary Thyroid Carcinoma Progression

1 Nov 2021

Abstract excerpt

Background Despite extensive research, the papillary thyroid carcinoma (PTC) ecosystem is poorly characterized and, in particular, locoregional progression. Available evidence supports that single-cell transcriptome sequencing (Sc-RNA seq) can dissect tumor ecosystems. Methods Tissue samples from one PTC patient, including matched primary tumor (Ca), lymph node (LN) metastasis, and paracancerous tissue (PCa),...

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PMID: 34790166
DOI: 10.3389/fendo.2021.729565

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