Article
Systematic exploration of Escherichia coli phage-host interactions with the BASEL phage collection.
PLoS biology - 1 Nov 2021
Maffei Enea, Shaidullina Aisylu, Burkolter Marco, Heyer Yannik, Estermann Fabienne, Druelle Valentin, Sauer Patrick, Willi Luc, Michaelis Sarah, Hilbi Hubert, Thaler David S, Harms Alexander
Abstract excerpt
Bacteriophages, the viruses infecting bacteria, hold great potential for the treatment of multidrug-resistant bacterial infections and other applications due to their unparalleled diversity and recent breakthroughs in their genetic engineering. However, fundamental knowledge of the molecular mechanisms underlying phage-host interactions is mostly confined to a few traditional model systems and did not keep pace...
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