A novel T4- and λ-based receptor binding protein family for bacteriophage therapy host range engineering

Abstract excerpt

Widespread multidrug antimicrobial resistance in emerging pathogens has led to a renewed interest in phage therapy as an alternative or supplement to traditional small molecule drugs. The primary limiting factors of phage therapy deployment rest in the narrow host range specificity of phage as well as a poor understanding of many phages’ unintended downstream effects on host physiology and microbiota as well as...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Bacteriophages and microbial interactions
• Share to Microbial infections and disease research
• Share to Monoclonal and Polyclonal Antibodies Research