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Article

PARP Inhibitors in Combination with Radiotherapy: To Do or Not to Do?

27 Oct 2021

Abstract excerpt

BACKGROUND: Despite the large use of inhibitors of Poly-ADP ribose polymerase (PARP-I), the feasibility and safety of their combination with radiotherapy (RT) is unclear. AIM: We conducted a literature analysis with the aim to evaluate the efficacy and safety profile of a combination with RT and PARP-I. METHOD: The key issues for the current review were expressed in two questions according to the Population,...

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PMID: 34771545
DOI: 10.3390/cancers13215380

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