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The -308G>a polymorphism of the TNF gene is associated with proliferative diabetic retinopathy in Caucasian Brazilians with type 2 diabetes.

Investigative ophthalmology & visual science - 29 Jan 2015

Sesti Luís F C, Crispim Daisy, Canani Luís H, Polina Evelise R, Rheinheimer Jakeline, Carvalho Patrícia S, Gross Jorge L, Santos Kátia G

Abstract excerpt

PURPOSE: We tested the hypothesis that tumor necrosis factor (TNF) gene polymorphisms are associated with diabetic retinopathy (DR) in Caucasians with type 2 diabetes mellitus. METHODS: In a case-control study, the -238G>A (rs361525), -308G>A (rs1800629), and -857C>T (rs1799724) polymorphisms of the TNF gene were genotyped in 745 outpatients with type 2 diabetes, including 331 subjects without DR, 246 with...

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PMID: 25634985
DOI: 10.1167/iovs.14-15758

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TNF

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The -308G>a polymorphism of the TNF gene is associated with proliferative diabetic retinopathy in Caucasian Brazilians with type 2 diabetes.PMID 25634985Read ↗

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