Article
Comparison of Transcranial Sonography and [18 F]-Fluorodopa PET Imaging in GBA1 Mutation Carriers.
Movement disorders : official journal of the Movement Disorder Society - 1 Mar 2022
Eisenberg Daniel P, Lopez Grisel, Gregory Michael D, Berman Karen F, Sidransky Ellen
Abstract excerpt
BACKGROUND: Mutations in GBA1 are a common genetic risk factor for parkinsonism; however, penetrance is incomplete, and biomarkers of future progression to parkinsonism are needed. Both nigral sonography and striatal [18 F]-FDOPA PET assay dopamine system health, but their utility and coherence in this context are unclear. OBJECTIVE: The aim of this study is to evaluate the utility and coherence of these...
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