Article
Genomic diversity and molecular dynamics interaction on mutational variances among RB domains of SARS-CoV-2 interplay drug inactivation.
Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases - 1 Jan 2022
Uddin Md Bashir, Sajib Emran Hossain, Hoque Syeda Farjana, Bappy Md Nazmul Islam, Elahi Fazle, Ghosh Arabinda, Muhit Samuel, Hassan Mohammad Mahmudul, Hasan Mahmudul, Chelliah Ramachandran, Park Se Jin, Mony Tamanna Jahan, Oh Deog-Hwan, Ahmed Syed Sayeem Uddin
Abstract excerpt
The scientific community has been releasing whole genomic sequences of SARS-CoV-2 to facilitate the investigation of molecular features and evolutionary history. We retrieved 36 genomes of 18 prevalent countries of Asia, Europe and America for genomic diversity and mutational analysis. Besides, we studied mutations in the RBD regions of Spike (S) proteins to analyze the drug efficiency against these mutations. In...
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