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Article

Maternal background alters the penetrance of growth phenotypes and sex-specific placental adaptation of offspring sired by alcohol-exposed males.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology - 1 Dec 2021

Thomas Kara N, Zimmel Katherine N, Roach Alexis N, Basel Alison, Mehta Nicole A, Bedi Yudhishtar S, Golding Michael C

Abstract excerpt

Epigenetic mechanisms of paternal inheritance are an emerging area of interest in our efforts to understand fetal alcohol spectrum disorders. In rodent models examining maternal alcohol exposures, different maternal genetic backgrounds protect or sensitize offspring to alcohol-induced teratogenesis. However, whether maternal background can mitigate sperm-inherited alterations in developmental programming and...

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Identifiers

PMID: 34748230
DOI: 10.1096/fj.202101131R
PMCID: PMC8713293

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

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