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Phylogenetic Analysis Indicates That Evasin-Like Proteins of Ixodid Ticks Fall Into Three Distinct Classes

22 Oct 2021

Abstract excerpt

Chemokines are structurally related proteins that activate leucocyte migration in response to injury or infection. Tick saliva contains chemokine-binding proteins or evasins which likely neutralize host chemokine function and inflammation. Biochemical characterisation of 50 evasins fromIxodes,AmblyommaandRhipicephalusshows that they fall into two functional classes, A and B, with exclusive binding to either CC-...

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PMID: 34746035
DOI: 10.3389/fcimb.2021.769542

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