Article
Radiogenomics Map Reveals the Landscape of m6A Methylation Modification Pattern in Bladder Cancer.
Frontiers in immunology - 1 Jan 2021
Ye Fangdie, Hu Yun, Gao Jiahao, Liang Yingchun, Liu Yufei, Ou Yuxi, Cheng Zhang, Jiang Haowen
Abstract excerpt
We aimed to develop a noninvasive radiomics approach to reveal the m6A methylation status and predict survival outcomes and therapeutic responses in patients. A total of 25 m6A regulators were selected for further analysis, we confirmed that expression level and genomic mutations rate of m6A regulators were significantly different between cancer and normal tissues. Besides, we constructed methylation modification...
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