Article
m6A regulator-mediated methylation modification patterns and characteristics of immunity and stemness in low-grade glioma.
Briefings in bioinformatics - 2 Sept 2021
Du Jianyang, Ji Hang, Ma Shuai, Jin Jiaqi, Mi Shan, Hou Kuiyuan, Dong Jiawei, Wang Fang, Zhang Chaochao, Li Yuan, Hu Shaoshan
Abstract excerpt
m6A RNA methylation is an emerging epigenetic modification, and its potential role in immunity and stemness remains unknown. Based on 17 widely recognized m6A regulators, the m6A modification patterns and corresponding characteristics of immune infiltration and stemness of 1152 low-grade glioma samples were comprehensively analyzed. Machine-learning strategies for constructing m6AScores were trained to quantify...
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