Article
Generation and Effect Testing of a SARS-CoV-2 RBD-Targeted Polyclonal Therapeutic Antibody Based on a 2-D Airway Organoid Screening System.
Frontiers in immunology - 1 Jan 2021
He Yunjiao, Qu Jing, Wei Lan, Liao Shumin, Zheng Nianzhen, Liu Yingzi, Wang Xingyun, Jing Yue, Shen Clifton Kwang-Fu, Ji Chong, Luo Guxun, Zhang Yiyun, Xiang Qi, Fu Yang, Li Shuo, Fan Yunping, Fang Shisong, Wang Peng, Li Liang
Abstract excerpt
Coronavirus disease 2019 (COVID-19) is an acute respiratory infectious disease caused by infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The US FDA has approved several therapeutics and vaccines worldwide through the emergency use authorization in response to the rapid spread of COVID-19. Nevertheless, the efficacies of these treatments are being challenged by viral escape mutations....
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