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Role of autophagy in lung diseases and ageing

21 Dec 2022

Abstract excerpt

The lungs face ongoing chemical, mechanical, biological, immunological and xenobiotic stresses over a lifetime. Advancing age progressively impairs lung function. Autophagy is a "housekeeping" survival strategy involved in numerous physiological and pathological processes in all eukaryotic cells. Autophagic activity decreases with age in several species, whereas its basic activity extends throughout the lifespan...

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PMID: 36543345
DOI: 10.1183/16000617.0134-2022

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