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Article

Identification of key genes involved in Brg1 mutation-induced cataract using bioinformatics analyses with publicly available microarray data.

Acta biochimica Polonica - 3 Nov 2021

Li Chen, Li Jianqing, Lu Peirong

Abstract excerpt

BACKGROUND: Cataract is a common and frequently occurring disease in the elderly. The Brahma-related gene 1 (Brg1) is believed to be related to the formation of cataract, but its mechanisms still remain unclear. This study aimed to investigate how a Brg1 mutation affects lens development and promotes the formation of cataract in mice. METHODS: We used mRNA profiles downloaded from the Gene Expression Omnibus...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 34731561
DOI: 10.18388/abp.2020_5632

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