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Article

A comprehensive modular map of molecular interactions in RB/E2F pathway.

Molecular systems biology - 1 Jan 2008

Calzone Laurence, Gelay Amélie, Zinovyev Andrei, Radvanyi François, Barillot Emmanuel

Abstract excerpt

We present, here, a detailed and curated map of molecular interactions taking place in the regulation of the cell cycle by the retinoblastoma protein (RB/RB1). Deregulations and/or mutations in this pathway are observed in most human cancers. The map was created using Systems Biology Graphical Notation language with the help of CellDesigner 3.5 software and converted into BioPAX 2.0 pathway description format. In...

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Identifiers

PMID: 18319725
DOI: 10.1038/msb.2008.7
PMCID: PMC2290939

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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