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Targeted Proteomics Profiling for Biomarker Discovery in Glaucoma Using the Olink Proteomics Platform

25 Sept 2024

Abstract excerpt

Metabolic dysfunction plays a crucial role in the pathogenesis of glaucoma. In this study, we used Olink proteomics profiling to identify potential biomarkers for glaucoma. Aqueous humor samples were obtained from 44 cataract patients and 44 glaucoma patients. We identified 84 differentially expressed metabolic proteins between the glaucoma and the cataract group. Gene Ontology enrichment analysis highlighted the...

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PMID: 39319515
DOI: 10.1021/acs.jproteome.4c00593

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