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Article

SLAMF8 expression predicts the efficacy of anti‐PD1 immunotherapy in gastrointestinal cancers

1 Jan 2021

Abstract excerpt

Abstract Objectives Epstein–Barr virus (EBV) infection is associated with a better response to anti‐PD1 immunotherapy. We hypothesised that genetic alterations induced by EBV infection are responsible for the activation of key immune responses and hence are predictive of anti‐PD1 efficacy. Methods With transcriptome data of gastric cancer (GC), we explored differentially expressed genes (DEGs) specific for EBV...

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PMID: 34729183
DOI: 10.1002/cti2.1347

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