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Article

Functional precision oncology: Testing tumors with drugs to identify vulnerabilities and novel combinations.

Cancer cell - 10 Jan 2022

Letai Anthony, Bhola Patrick, Welm Alana L

Abstract excerpt

Functional precision medicine is a strategy whereby live tumor cells from affected individuals are directly perturbed with drugs to provide immediately translatable, personalized information to guide therapy. The heterogeneity of human cancer has led to the realization that personalized approaches are needed to improve treatment outcomes. Precision oncology has traditionally used static features of the tumor to...

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Identifiers

PMID: 34951956
DOI: 10.1016/j.ccell.2021.12.004
PMCID: PMC8752507

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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