Article
Activation of oxidative phosphorylation in TP53-inactive endometrial carcinomas with a poor prognosis.
International journal of gynecological cancer : official journal of the International Gynecological Cancer Society - 1 Dec 2021
Takahashi Nobutaka, Hatakeyama Keiichi, Nagashima Takeshi, Ohshima Keiichi, Urakami Kenichi, Yamaguchi Ken, Hirashima Yasuyuki
Abstract excerpt
OBJECTIVE: We aimed to identify pathways for potential therapeutic targets by conducting molecular profiling of endometrial carcinomas in patients with poor prognosis. METHODS: The classification of endometrial carcinomas has undergone a paradigm shift with the advent of next generation sequencing based molecular profiling. Although this emerging classification reflects poor prognosis in patients with endometrial...
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