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HLA alleles measured from COVID-19 patient transcriptomes reveal associations with disease prognosis in a New York cohort

15 Oct 2021

Abstract excerpt

Background The Human Leukocyte Antigen (HLA) gene locus plays a fundamental role in human immunity, and it is established that certain HLA alleles are disease determinants. Previously, we have identified prevalent HLA class I and class II alleles, including DPA1*02:02, in two small patient cohorts at the COVID-19 pandemic onset. Methods We have since analyzed a larger public patient cohort data ( n = 126...

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PMID: 34722002
DOI: 10.7717/peerj.12368

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