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Article

miR-20a Overexpression in Adipose-Derived Mesenchymal Stem Cells Promotes Therapeutic Efficacy in Murine Lupus Nephritis by Regulating Autophagy

21 Oct 2021

Abstract excerpt

OBJECTIVE: Lupus nephritis is the most common and severe complication of systemic lupus erythematosus. The aim of our study was to investigate the efficacy of miR-20a overexpressing adipose-derived stem cell (ADSC) transplantation in murine lupus nephritis (LN) and explore potential molecular mechanisms. METHODS: . B6.MRL/lpr mice were administered ADSC/miR-20a-ADSC intravenously every week from age 30 to 33...

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PMID: 34721589
DOI: 10.1155/2021/3746335

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