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A Dual, Systematic Approach to Malaria Diagnostic Biomarker Discovery

30 Sept 2021

Abstract excerpt

BACKGROUND: The emergence and spread of Plasmodium falciparum parasites that lack HRP2/3 proteins and the resulting decreased utility of HRP2-based malaria rapid diagnostic tests (RDTs) prompted the World Health Organization and other global health stakeholders to prioritize the discovery of novel diagnostic biomarkers for malaria. METHODS: To address this pressing need, we adopted a dual, systematic approach by...

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PMID: 34718455
DOI: 10.1093/cid/ciab251

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