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Genomic Insights Into Nitrofurantoin Resistance Mechanisms and Epidemiology in Clinical Enterobacteriaceae

27 Feb 2018

Abstract excerpt

Aim: Multidrug-resistant enterobacteria are highly associated with invasive devices and intensive care units. Increasing resistance to carbapenems is leading to the use of older and neglected antibiotics such as nitrofurantoin (NFT). The genomics of NFT resistance was investigated. Results & conclusion: High-level resistance to NFT (minimum inhibitory concentration ≥128–512 mg/l) was recorded in 31/36 isolates...

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Identifiers

PMID: 29796297
DOI: 10.4155/fsoa-2017-0156

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