Article
Molecular surveillance and genetic divergence of rotavirus A antigenic epitopes in Gabonese children with acute gastroenteritis.
EBioMedicine - 1 Nov 2021
Manouana Gédéon Prince, Niendorf Sandra, Tomazatos Alexandru, Mbong Ngwese Mirabeau, Nzamba Maloum Moustapha, Nguema Moure Paul Alvyn, Bingoulou Matsougou Gedeon, Ategbo Simon, Rossatanga Elie Gide, Bock C Thomas, Borrmann Steffen, Mordmüller Benjamin, Eibach Daniel, Kremsner Peter G, Velavan Thirumalaisamy P, Adegnika Ayola Akim
Abstract excerpt
BACKGROUND: Rotavirus A (RVA) causes acute gastroenteritis in children <5 years of age in sub-Saharan Africa. In this study, we described the epidemiology and genetic diversity of RVA infecting Gabonese children and examined the antigenic variability of circulating strains in relation to available vaccine strains to maximize the public health benefits of introducing rotavirus vaccine through the Expanded...
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