Article
Comparative genomic analysis of genogroup 1 (Wa-like) rotaviruses circulating in the USA, 2006-2009.
Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases - 1 Dec 2014
Roy Sunando, Esona Mathew D, Kirkness Ewen F, Akopov Asmik, McAllen J Kyle, Wikswo Mary E, Cortese Margaret M, Payne Daniel C, Parashar Umesh D, Gentsch Jon R, Bowen Michael D
Abstract excerpt
Group A rotaviruses (RVA) are double stranded RNA viruses that are a significant cause of acute pediatric gastroenteritis. Beginning in 2006 and 2008, respectively, two vaccines, Rotarix™ and RotaTeq®, have been approved for use in the USA for prevention of RVA disease. The effects of possible vaccine pressure on currently circulating strains in the USA and their genome constellations are still under...
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