Group A rotaviruses circulating prior to a national immunization programme in Nigeria: Clinical manifestations, high G12P[8] frequency, intra-genotypic divergence of VP4 and VP7.

doi:10.1002/jmv.24949

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Article

Group A rotaviruses circulating prior to a national immunization programme in Nigeria: Clinical manifestations, high G12P[8] frequency, intra-genotypic divergence of VP4 and VP7.

Journal of medical virology - 1 Feb 2018

Japhet Margaret O, Famurewa Oladiran, Iturriza-Gomara Miren, Adesina Olufisayo A, Opaleye Oluyinka O, Niendorf Sandra, Bock C Thomas, Mas Marques Andreas

Abstract excerpt

Nigeria having approximately 50 000 Rotavirus A (RVA) deaths annually is yet to introduce RVA vaccine into routine national immunization; therefore surveillance of RVA strains circulating before vaccine introduction is essential in evaluating impact of the intervention. Stool samples and sociodemographic data of diarrhoeic children, <5 years were collected between August 2012 and December 2013. While a high...

Topics

Antigens, Viral
Capsid Proteins
Child, Preschool
Feces
Female
Genetic Variation
Genotype
Humans
Infant
Infant, Newborn

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Male

Molecular Epidemiology

Nigeria

Prevalence

Real-Time Polymerase Chain Reaction

Reverse Transcriptase Polymerase Chain Reaction

Rotavirus

Rotavirus Infections

Source

Open in PubMed

Identifiers

PMID: 28906005
DOI: 10.1002/jmv.24949

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