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Article

SARS-CoV-2 variant with mutations in N gene affecting detection by widely used PCR primers.

Journal of medical virology - 1 Mar 2022

Laine Pia, Nihtilä Hanna, Mustanoja Ella, Lyyski Annina, Ylinen Anne, Hurme Jukka, Paulin Lars, Jokiranta Sakari, Auvinen Petri, Meri Taru

Abstract excerpt

While most of the spontaneous mutations in the viral genome have no functional, diagnostic, or clinical consequences, some have. In February 2021, we noticed in Southern Finland coronavirus disease 2019 cases where two commercial polymerase chain reaction (PCR) analyses failed to recognize the used N gene target but recognized the other target gene of severe acute respiratory syndrome coronavirus 2. Complete...

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Identifiers

PMID: 34698407
DOI: 10.1002/jmv.27418
PMCID: PMC8661661

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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