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Article

A novel single nucleotide polymorphism assay for the detection of N501Y SARS-CoV-2 variants.

Journal of virological methods - 1 Aug 2021

Sandoval Torrientes M, Castelló Abietar C, Boga Riveiro J, Álvarez-Argüelles M E, Rojo-Alba S, Abreu Salinas F, Costales González I, Pérez Martínez Z, Martín Rodríguez G, Gómez de Oña J, Coto García E, Melón García S

Abstract excerpt

The N501Y mutation in SARS-CoV-2 variants found in several strains from the UK, South Africa and Brazil has been linked to increased transmission. In order to discriminate N501Y variants quickly, a single nucleotide polymorphism (SNP) discrimination assay was designed and validated. It was then deployed prospectively in 757 nasopharyngeal swabs. Validation of the novel variant discrimination assay corroborated...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 33774075
DOI: 10.1016/j.jviromet.2021.114143
PMCID: PMC7989071

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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