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Construction, Characterization and Application of Recombinant Porcine Deltacoronavirus Expressing Nanoluciferase

4 Oct 2021

Abstract excerpt

Porcine deltacoronavirus (PDCoV), an emerging enteropathogenic coronavirus, causes diarrhoea in suckling piglets and has the potential for cross-species transmission. No effective PDCoV vaccines or antiviral drugs are currently available. Here, we successfully generated an infectious clone of PDCoV strain CHN-HN-2014 using a combination of bacterial artificial chromosome (BAC)-based reverse genetics system with a...

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PMID: 34696421
DOI: 10.3390/v13101991

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