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Generation of G9 genotype porcine rotavirus using reverse genetics system and its application for antiviral screen and vaccine development.

Virologica Sinica - 1 Apr 2026

Han Nan, Tao Ran, Cheng Xi, Deng Hui, Wang Jianxin, Bian Xianyu, Zhou Jinzhu, Zhu Xuejiao, Sun Min, Zhang Xuehan, Hu Mi, Guo Rongli, Wang Wei, Ding Siyuan, Li Bin

Abstract excerpt

Group A rotaviruses (RVs) continue to be one of the most important pathogens causing severe acute gastroenteritis in infants and young animals worldwide. Recently, the prevalence of porcine RV (PoRV) from pig farms has strikingly increased, adversely affecting the swine industry, particularly with the G9 genotype of PoRV VP7 emerging as the predominant genotype spreading in China. Current vaccines against PoRV...

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Antibodies, Viral
Antigens, Viral
Reassortant Viruses
Reverse Genetics
Rotavirus

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Rotavirus Infections

Rotavirus Vaccines

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Open in PubMed Open full text

Identifiers

PMID: 41997488
DOI: 10.1016/j.virs.2026.04.005
PMCID: PMC13215963

Genes

C9

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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