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Development of a DNA-launched reverse genetics system for a highly virulent porcine deltacoronavirus and infectious dose-dependent characterization of a rescued virus in vivo

2026-08-21

Abstract excerpt

<title>Abstract</title> <p> Porcine deltacoronavirus (PDCoV) poses a growing threat to animal health and the pig industry. Given the scarcity of vaccines and antivirals targeting PDCoV, versatile and broadly adopted research techniques, such as reverse genetics (RG), are critical for understanding its biology and pathogenesis. In this study, we constructed a DNA-launched infectious cDNA clone of the highly patho...

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Literature Corpus work
55317f75-c04d-5d44-b2d5-58f0bb4cbaa1
DOI
10.21203/rs.3.rs-10677640/v1
Open publication

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Development of a DNA-launched reverse genetics system for a highly virulent porcine deltacoronavirus and infectious dose-dependent characterization of a rescued virus in vivoDOI 10.21203/rs.3.rs-10677640/v1
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