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Article

Epigenetic priming in neurodevelopmental disorders.

Trends in molecular medicine - 1 Dec 2021

Ernst Carl, Jefri Malvin

Abstract excerpt

Neurodevelopmental disorders (NDDs) affect about 1% of the population and can be caused by mutations in genes that affect the epigenetic code. There is limited functional understanding of most of these epigenetic modifiers, and we suggest that associated NDDs are caused, in part, by deficits in epigenetic priming, a prepatterning step that alters the genome in preparation to make cells competent to signaling...

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Identifiers

PMID: 34690045
DOI: 10.1016/j.molmed.2021.09.005

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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