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Article

Prediction of the differences in tumor mutation burden between primary and metastatic lesions by radiogenomics.

Cancer science - 1 Jan 2022

Hoshino Isamu, Yokota Hajime, Iwatate Yosuke, Mori Yasukuni, Kuwayama Naoki, Ishige Fumitaka, Itami Makiko, Uno Takashi, Nakamura Yuki, Tatsumi Yasutoshi, Shimozato Osamu, Nagase Hiroki

Abstract excerpt

Tumor mutational burden (TMB) is gaining attention as a biomarker for responses to immune checkpoint inhibitors in cancer patients. In this study, we evaluated the status of TMB in primary and liver metastatic lesions in patients with colorectal cancer (CRC). In addition, the status of TMB in primary and liver metastatic lesions was inferred by radiogenomics on the basis of computed tomography (CT) images. The...

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Identifiers

PMID: 34689378
DOI: 10.1111/cas.15173
PMCID: PMC8748253

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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