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Article

A Recurrent STAT5BN642H Driver Mutation in Feline Alimentary T Cell Lymphoma

19 Oct 2021

Abstract excerpt

Alimentary lymphomas arising from T cells are rare and aggressive malignancies in humans. In comparison, they represent the most common anatomical form of lymphoma in cats. Due to the low prevalence in humans, the underlying pathomechanism for these diseases is poorly characterised, limiting experimental analysis and therapeutic exploration. To date, activating mutations of the JAK/STAT core cancer pathway and...

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PMID: 34680385
DOI: 10.3390/cancers13205238

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