Article
Next-generation sequencing of human respiratory syncytial virus subgroups A and B genomes.
Journal of virological methods - 1 Jan 2022
Wang Lijuan, Ng Terry Fei Fan, Castro Christina J, Marine Rachel L, Magaña Laura C, Esona Mathew, Peret Teresa C T, Thornburg Natalie J
Abstract excerpt
Human respiratory syncytial virus (HRSV) is a leading cause of acute respiratory illness in young children worldwide. Whole genome sequencing of HRSV offers enhanced resolution of strain variability for epidemiological surveillance and provides genomic information essential for antiviral and vaccine development. A 10-amplicon one-step RT-PCR assay and a 20-amplicon nested RT-PCR assay with enhanced sensitivity...
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