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Genome-Wide Analyses of Human Respiratory Syncytial Viruses Provide Insights into Evolutionary Dynamics.

Genome biology and evolution - 30 Apr 2025

Chen Lu-Lu, Tong Chu-Ci, Zhao Yu-Xian, Zheng Yan-Peng, Peng Xiang-Lei, Fu Yuan-Hui, He Jin-Sheng, Yu Jie-Mei

Abstract excerpt

Human Respiratory syncytial virus (HRSV) is a leading cause of acute lower respiratory tract infections. It is essential to monitor its genomic characteristics. In this study, we analyzed the variation and evolutionary features of HRSV A and HRSV B using whole-genome data, with a focus on their evolutionary features post-COVID-19. Our findings revealed: (i) the mutation rates of HRSV A genes were generally higher...

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Identifiers

PMID: 40418624
DOI: 10.1093/gbe/evaf093
PMCID: PMC12120135

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