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Article

AGO2 expression levels and related genetic polymorphisms: influence in renal cell progression and aggressive phenotypes.

Pharmacogenomics - 1 Nov 2021

Teixeira Ana Luísa, Patrão Ana Sofia, Dias Francisca, Silva Carlos, Vieira Isabel, Silva José Fernando, Ferreira Marta, Morais António, Maurício Joaquina, Medeiros Rui

Abstract excerpt

Aim: Renal cell carcinoma (RCC) is the most lethal urological cancer and up to 40% of patients submitted to surgery will relapse. Thus, the study aim was to analyze the associations of AGO2 SNPs with RCC patients' prognosis, and evaluate their effect on AGO2 mRNA levels. Materials & methods: The AGO2 rs4961280, rs3928672 and rs11996715 polymorphisms and the relative quantification of AGO2 mRNA levels were...

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Identifiers

PMID: 34672687
DOI: 10.2217/pgs-2021-0072

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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