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Unconventional Actions of Glycoprotein Hormone Subunits: A Comprehensive Review

21 Sept 2021

Abstract excerpt

The glycoprotein hormones (GPH) are heterodimers composed of a common α subunit and a specific β subunit. They act by activating specific leucine-rich repeat G protein-coupled receptors. However, individual subunits have been shown to elicit responses in cells devoid of the receptor for the dimeric hormones. The α subunit is involved in prolactin production from different tissues. The human chorionic gonadotropin...

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PMID: 34671318
DOI: 10.3389/fendo.2021.731966

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