Molecular Basis of the Specificity of Binding of Glycoprotein Hormones to Their Receptors

doi:10.1210/edrv-13-4-670

Article

Molecular Basis of the Specificity of Binding of Glycoprotein Hormones to Their Receptors

1 Nov 1992

Abstract excerpt

THREE glycoprotein hormones are synthesized and secreted by the pituitary under hypothalamic control. Two of them are the gonadotropins, LH and FSH, and the third one is TSH. During gestation in primates and equidaes an additional gonadotropin, CG, is secreted by the placenta. Pituitary gonadotropins play pivotal roles in the control of reproductive function in both the female (1, 2) and the male (3) while the...

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