Article
Immunohistochemical expression and neurochemical phenotypes of huntingtin-associated protein 1 in the myenteric plexus of mouse gastrointestinal tract.
Cell and tissue research - 1 Dec 2021
Tarif Abu Md Mamun, Islam Md Nabiul, Jahan Mir Rubayet, Yanai Akie, Nozaki Kanako, Masumoto Koh-Hei, Shinoda Koh
Abstract excerpt
Huntingtin-associated protein 1 (HAP1) is a neural huntingtin interactor and being considered as a core molecule of stigmoid body (STB). Brain/spinal cord regions with abundant STB/HAP1 expression are usually spared from neurodegeneration in stress/disease conditions, whereas the regions with little STB/HAP1 expression are always neurodegenerative targets. The enteric nervous system (ENS) can act as a potential...
Topics
- Animals
- DNA-Binding Proteins
- Gastrointestinal Tract
- Immunohistochemistry
- Male
- Mice
- Myenteric Plexus
- Phenotype
