Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Immunohistochemical expression and neurochemical phenotypes of huntingtin-associated protein 1 in the myenteric plexus of mouse gastrointestinal tract.

Cell and tissue research - 1 Dec 2021

Tarif Abu Md Mamun, Islam Md Nabiul, Jahan Mir Rubayet, Yanai Akie, Nozaki Kanako, Masumoto Koh-Hei, Shinoda Koh

Abstract excerpt

Huntingtin-associated protein 1 (HAP1) is a neural huntingtin interactor and being considered as a core molecule of stigmoid body (STB). Brain/spinal cord regions with abundant STB/HAP1 expression are usually spared from neurodegeneration in stress/disease conditions, whereas the regions with little STB/HAP1 expression are always neurodegenerative targets. The enteric nervous system (ENS) can act as a potential...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to DNA-Binding Proteins
Share to Gastrointestinal Tract

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Immunohistochemistry

Share to Phenotype

Source

Identifiers

PMID: 34665322
DOI: 10.1007/s00441-021-03542-4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Immunohistochemical expression and neurochemical phenotypes of huntingtin-associated protein 1 in the myenteric plexus of mouse gastrointestinal tract.PMID 34665322Read ↗

Neurochemical phenotypes of huntingtin-associated protein 1 in reference to secretomotor and vasodilator neurons in the submucosal plexuses of rodent small intestine.Semantic proximity Read ↗

Lack of huntingtin-associated protein-1 causes neuronal death resembling hypothalamic degeneration in Huntington's disease.Semantic proximity Read ↗

Ascl1 Is Required for the Development of Specific Neuronal Subtypes in the Enteric Nervous System.Semantic proximity Read ↗

Investigation of general and cytoskeletal markers to estimate numbers and proportions of neurons in the human intestine.Semantic proximity Read ↗

Similarities and differences between nigral and enteric dopaminergic neurons unravel distinctive involvement in Parkinson’s diseaseSemantic proximity Read ↗

Huntingtin-interacting protein 1 influences worm and mouse presynaptic function and protects Caenorhabditis elegans neurons against mutant polyglutamine toxicity.Semantic proximity Read ↗

Differential Regional and Subtype-Specific Vulnerability of Enteric Neurons to Mitochondrial DysfunctionSemantic proximity Read ↗

Intertwining Neuropathogenic Impacts of Aberrant Circadian Rhythm and Impaired Neuroregenerative Plasticity in Hutington’s Disease: Neurotherapeutic Significance of ChemogeneticsSemantic proximity Read ↗

Loss of huntingtin-associated protein 1 impairs insulin secretion from pancreatic β-cells.Semantic proximity Read ↗

Diagnosing Neurodegenerative Diseases by Label-Free 3-D Imaging of Intestinal SamplesSemantic proximity Read ↗

Distinct histological alterations of cortical interneuron types in mouse models of Huntington’s diseaseSemantic proximity Read ↗

Characterization and transplantation of enteric neural crest cells from human induced pluripotent stem cellsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.