Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Beyond Ca2+ signalling: the role of TRPV3 in the transport of NH4.

Pflugers Archiv : European journal of physiology - 1 Dec 2021

Liebe Hendrik, Liebe Franziska, Sponder Gerhard, Hedtrich Sarah, Stumpff Friederike

Abstract excerpt

Mutations of TRPV3 lead to severe dermal hyperkeratosis in Olmsted syndrome, but whether the mutants are trafficked to the cell membrane or not is controversial. Even less is known about TRPV3 function in intestinal epithelia, although research on ruminants and pigs suggests an involvement in the uptake of NH4+. It was the purpose of this study to measure the permeability of the human homologue (hTRPV3) to NH4+,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Ammonia
Share to Calcium Signaling
Share to Cell Membrane Permeability

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Epithelium

Share to Keratinocytes

Share to Patch-Clamp Techniques

Share to TRPV Cation Channels

Share to Xenopus laevis

Source

Open in PubMed Open full text

Identifiers

PMID: 34664138
DOI: 10.1007/s00424-021-02616-0
PMCID: PMC8599221

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Beyond Ca2+ signalling: the role of TRPV3 in the transport of NH4.PMID 34664138Read ↗

TRPV3 Ion Channel: From Gene to PharmacologySemantic proximity Read ↗

TRPV3: a 'more than skinny' channel.Semantic proximity Read ↗

TRPV3 mutants causing Olmsted Syndrome induce impaired cell adhesion and nonfunctional lysosomes.Semantic proximity Read ↗

Roles of Aquaporin-3 in the EpidermisSemantic proximity Read ↗

TRPV3.Semantic proximity Read ↗

Neutral amino acid transport in epithelial cells and its malfunction in Hartnup disorderSemantic proximity Read ↗

TRPV3: time to decipher a poorly understood family member!Semantic proximity Read ↗

Functional assessment of SLC4A11, an integral membrane protein mutated in corneal dystrophies.Semantic proximity Read ↗

Function of the HVCN1 proton channel in airway epithelia and a naturally occurring mutation, M91T.Semantic proximity Read ↗

A novel mode of TRPML3 regulation by extracytosolic pH absent in the varitint-waddler phenotype.Semantic proximity Read ↗

The amino-terminal domain of TRPV4 channel is involved in its trafficking to the nucleus.Semantic proximity Read ↗

Involvement of TRPV4 in temperature-dependent perspiration in miceSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.