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Inhibiting microcephaly genes as alternative to microtubule targeting agents to treat brain tumors

18 Oct 2021

Abstract excerpt

Medulloblastoma (MB) and gliomas are the most frequent high-grade brain tumors (HGBT) in children and adulthood, respectively. The general treatment for these tumors consists in surgery, followed by radiotherapy and chemotherapy. Despite the improvement in patient survival, these therapies are only partially effective, and many patients still die. In the last decades, microtubules have emerged as interesting...

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Share to Epigenetics and DNA Methylation
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PMID: 34663805
DOI: 10.1038/s41419-021-04259-6

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