Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Mendelian randomization study of coffee consumption and age at onset of Huntington's disease.

Clinical nutrition (Edinburgh, Scotland) - 1 Nov 2021

Wang Mengmeng, Cornelis Marilyn C, Zhang Zhizhong, Liu Dandan, Lian Xuegan

Abstract excerpt

BACKGROUND & AIM: The association between habitual coffee or caffeine consumption and age at onset (AAO) of Huntington's disease (HD) is unclear. We employed Mendelian randomization to investigate the causal relationship between coffee consumption and AAO of HD. METHODS: The instrumental variable including 14 independent genetic variants associated with coffee consumption was selected from a genome-wide...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Age of Onset
Share to Causality
Share to Coffee

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Drinking

Share to Genome-Wide Association Study

Share to Huntington Disease

Share to Mendelian Randomization Analysis

Share to White People

Source

Open in PubMed Open full text

Identifiers

PMID: 34656958
DOI: 10.1016/j.clnu.2021.09.041
PMCID: PMC10547005

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Mendelian randomization study of coffee consumption and age at onset of Huntington's disease.PMID 34656958Read ↗

Smoking, alcohol consumption, and age at onset of Huntington's disease: a Mendelian randomization study.Semantic proximity Read ↗

Mendelian Randomization Studies of Coffee and Caffeine ConsumptionSemantic proximity Read ↗

Coffee consumption is associated with later age-at-onset of Parkinson’s diseaseSemantic proximity Read ↗

Habitual Coffee Consumption Increases Risks for Metabolic Diseases: Genome-wide Association Studies and a Phenotype-wide Two Sample Mendelian Randomization AnalysisSemantic proximity Read ↗

Habitual Coffee Consumption Increases Risk of Primary Open-Angle Glaucoma: A Mendelian Randomization Study.Semantic proximity Read ↗

Tendency towards being a “Morning person” increases risk of Parkinson’s disease: evidence from Mendelian randomisationSemantic proximity Read ↗

The Genetic Modifiers of Motor OnsetAge (GeM MOA) Website: Genome-wide Association Analysis for Genetic Modifiers of Huntington's Disease.Semantic proximity Read ↗

A single nucleotide polymorphism in the coding region of PGC-1α is a male-specific modifier of Huntington disease age-at-onset in a large European cohort.Semantic proximity Read ↗

Population stratification may bias analysis of PGC-1α as a modifier of age at Huntington disease motor onset.Semantic proximity Read ↗

Causal relationship between coffee intake and neurological diseases: a Mendelian randomization studySemantic proximity Read ↗

Genetically predicted coffee consumption and amyotrophic lateral sclerosis.Semantic proximity Read ↗

Genetically Predicted Coffee Consumption and Risk of Alzheimer’s Disease and StrokeSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.