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Article

A novel mutation in PCK2 gene causes primary angle-closure glaucoma.

Aging - 14 Oct 2021

Xu Menghan, Yang Jin, Sun Jiayue, Xing Xuemei, Liu Zheng, Liu Tao

Abstract excerpt

Primary angle-closure glaucoma (PACG) is an ophthalmic genetic disease characterized by direct contact between the iris and trabecular meshwork, resulting in an obstructed outflow of aqueous humor from the eye. However, it is unclear as to what role genetics plays in the development of PACG. The present study investigated the disease-causing mutation in a five-generation Chinese PACG family using whole-genome...

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Identifiers

PMID: 34650006
DOI: 10.18632/aging.203627
PMCID: PMC8544327

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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