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Article

NuMorph: Tools for cortical cellular phenotyping in tissue-cleared whole-brain images.

Cell reports - 12 Oct 2021

Krupa Oleh, Fragola Giulia, Hadden-Ford Ellie, Mory Jessica T, Liu Tianyi, Humphrey Zachary, Rees Benjamin W, Krishnamurthy Ashok, Snider William D, Zylka Mark J, Wu Guorong, Xing Lei, Stein Jason L

Abstract excerpt

Tissue-clearing methods allow every cell in the mouse brain to be imaged without physical sectioning. However, the computational tools currently available for cell quantification in cleared tissue images have been limited to counting sparse cell populations in stereotypical mice. Here, we introduce NuMorph, a group of analysis tools to quantify all nuclei and nuclear markers within the mouse cortex after clearing...

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Identifiers

PMID: 34644582
DOI: 10.1016/j.celrep.2021.109802
PMCID: PMC8530274

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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