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Article

Role of African Swine Fever Virus Proteins EP153R and EP402R in Reducing Viral Persistence in Blood and Virulence in Pigs Infected with BeninΔDP148R.

Journal of virology - 12 Jan 2022

Petrovan Vlad, Rathakrishnan Anusyah, Islam Muneeb, Goatley Lynnette C, Moffat Katy, Sanchez-Cordon Pedro J, Reis Ana L, Dixon Linda K

Abstract excerpt

The limited knowledge on the role of many of the approximately 170 proteins encoded by African swine fever virus restricts progress toward vaccine development. Previously, the DP148R gene was deleted from the genome of genotype I virulent Benin 97/1 isolate. This virus, BeninΔDP148R, induced transient moderate clinical signs after immunization and high levels of protection against challenge. However, the...

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Identifiers

PMID: 34643433
DOI: 10.1128/JVI.01340-21
PMCID: PMC8754224

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