Article
Evaluation of protection induced by immunisation of domestic pigs with deletion mutant African swine fever virus BeninΔMGF by different doses and routes.
Vaccine - 29 Jan 2018
Sánchez-Cordón Pedro J, Jabbar Tamara, Berrezaie Margot, Chapman Dave, Reis Ana, Sastre Patricia, Rueda Paloma, Goatley Lynnette, Dixon Linda K
Abstract excerpt
A live attenuated African swine fever virus (ASFV) vaccine candidate, produced by deletion of several genes belonging to multi-gene families MGF360 and 505 from virulent Benin 97/1 strain (BeninΔMGF), induces protection in pigs against parental virulent strain. In order to better define the safety and efficacy of this attenuated vaccine candidate and to understand protective mechanisms, we extended previous...
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