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Development and validation of Kongoh ver. 3.0.1: Open-source software for DNA mixture interpretation in the GlobalFiler system based on a quantitative continuous model.

Legal medicine (Tokyo, Japan) - 1 Feb 2022

Manabe Sho, Fukagawa Takashi, Fujii Koji, Mizuno Natsuko, Sekiguchi Kazumasa, Akane Atsushi, Tamaki Keiji

Abstract excerpt

Probabilistic genotyping software based on continuous models is effective for interpreting DNA profiles derived from DNA mixtures and small DNA samples. In this study, we updated our previously developed Kongoh software (to ver. 3.0.1) to interpret DNA profiles typed using the GlobalFiler™ PCR Amplification Kit. Recently, highly sensitive typing systems such as the GlobalFiler system have facilitated the...

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PMID: 34629243
DOI: 10.1016/j.legalmed.2021.101972

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