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Validation of a top-down DNA profile analysis for database searching using a fully continuous probabilistic genotyping model.

Forensic science international. Genetics - 1 May 2021

Taylor Duncan, Bright Jo-Anne, Scandrett Lenara, Abarno Damien, Lee Shan-I, Wivell Richard, Kelly Hannah, Buckleton John

Abstract excerpt

Slooten described a method of targeting major contributors in mixed DNA profiles and comparing them to individuals on a DNA database. The method worked by taking incrementally more peak information from the profile (based on the peak contribution), and using a semi-continuous model, calculating likelihood ratios for the comparison to database individuals. We describe the performance of this "top down approach" to...

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PMID: 33588348
DOI: 10.1016/j.fsigen.2021.102479

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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