Article
Recognition of Philadelphia chromosome-like acute lymphoblastic leukemia as part of routine diagnostic work-up.
International journal of laboratory hematology - 1 Feb 2022
Podgornik Helena, Doplihar Kebe Ana, Klun Jurka, Reberšek Katarina, Šućurović Sandra, Škerget Matevž, Zver Samo
Abstract excerpt
INTRODUCTION: Philadelphia chromosome (Ph)-like acute lymphoblastic leukemia (ALL) is a biologically and clinically challenging subtype of B-cell ALL which has been incorporated into the 2016 revision of the World Health classification of acute leukemia. It is independently associated with poor outcome. As it can only be reliably detected by expression profiling, it is difficult to diagnose with routine methods....
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